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Inhibition of [(14)C]Chloramphenicol Binding to Escherichia coli Ribosomes by Erythromycin Derivatives

The effect of erythromycin A and 35 analogues of erythromycin A on [(14)C]chloramphenicol binding to Escherichia coli ribosomes was evaluated. Substitutions on various portions of the erythromycin molecule were made with retention of ability to bind to ribosomes. Specifically, substantial activity i...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Pestka, Sidney, LeMahieu, Ronald A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429045/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15828169/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.6.1.39
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