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Binding of [(14)C]Erythromycin to Escherichia coli Ribosomes

Erythromycin binding to Escherichia coli ribosomes required K(+) and Mg(2+). Under optimal conditions, the dissociation constant for erythromycin binding to E. coli ribosomes was found to be 1.0 × 10(−8) M and 1.4 × 10(−8) M at 24 C and 5 C, respectively. One molecule of [(14)C]erythromycin was boun...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Author: Pestka, Sidney
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1974
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444674/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4157348/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.6.4.474
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