Correlation of Effects of Erythromycin Analogues on Intact Bacteria and on [(14)C]Erythromycin Binding to Escherichia coli Ribosomes

The dissociation constants for binding to ribosomes from Escherichia coli and concentrations at which 50% inhibition of [(14)C]erythromycin binding to ribosomes occurred were determined for 45 erythromycin analogues. These values were correlated with their antibacterial activities against Bacillus s...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Pestka, Sidney, Lemahieu, Ronald, Miller, Philip
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1974
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444676/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4157350/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.6.4.489
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