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Molecular Basis for the Selective Toxicity of Amphotericin B for Yeast and Filipin for Animal Cells
Among the polyene antibiotics, many, like filipin, cannot be used clinically because they are toxic; amphotericin B, however, is useful in therapy of human fungal infections because it is less toxic. Both the toxicity of filipin and the therapeutic value of amphotericin B can be rationalized at the...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1974
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC428978/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15825391/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.5.4.377 |
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