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Quantifying the cost in power of ignoring continuous covariate imbalances in clinical trial randomization

Motivated by potentially serious imbalances of continuous baseline covariates in clinical trials, we investigated the cost in statistical power of ignoring the balance of these covariates in treatment allocation design for a logistic regression model. Based on data from a clinical trial of acute isc...

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Bibliographische Detailangaben
Veröffentlicht in:Contemp Clin Trials
Hauptverfasser: Ciolino, Jody, Zhao, Wenle, Martin, Renee’, Palesch, Yuko
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288592/
https://ncbi.nlm.nih.gov/pubmed/21078415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2010.11.005
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