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Continuous Covariate Imbalance and Conditional Power for Clinical Trial Interim Analyses
Oftentimes valid statistical analyses for clinical trials involve adjustment for known influential covariates, regardless of imbalance observed in these covariates at baseline across treatment groups. Thus, it must be the case that valid interim analyses also properly adjust for these covariates. Th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4024327/ https://ncbi.nlm.nih.gov/pubmed/24607294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2014.02.007 |
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