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Minimal sufficient balance—a new strategy to balance baseline covariates and preserve randomness of treatment allocation
In many clinical trials, baseline covariates could affect the primary outcome. Commonly used strategies to balance baseline covariates include stratified constrained randomization and minimization. Stratification is limited to few categorical covariates. Minimization lacks the randomness of treatmen...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474894/ https://ncbi.nlm.nih.gov/pubmed/22287602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280212436447 |
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