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Statistical issues in the use of dynamic allocation methods for balancing baseline covariates

BACKGROUND: The procedure for allocating patients to a treatment arm in comparative clinical trials is frequently chosen with only minor deliberation. This decision may, however, ultimately impact the trial inference, credibility, and even validity of the trial analysis. Cancer researchers are incre...

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Detalhes bibliográficos
Autor principal: Pond, G R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111167/
https://ncbi.nlm.nih.gov/pubmed/21540857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.157
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