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Quantifying the cost in power of ignoring continuous covariate imbalances in clinical trial randomization

Motivated by potentially serious imbalances of continuous baseline covariates in clinical trials, we investigated the cost in statistical power of ignoring the balance of these covariates in treatment allocation design for a logistic regression model. Based on data from a clinical trial of acute isc...

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Detalhes bibliográficos
Publicado no:Contemp Clin Trials
Main Authors: Ciolino, Jody, Zhao, Wenle, Martin, Renee’, Palesch, Yuko
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288592/
https://ncbi.nlm.nih.gov/pubmed/21078415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2010.11.005
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