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Quantifying the cost in power of ignoring continuous covariate imbalances in clinical trial randomization

Motivated by potentially serious imbalances of continuous baseline covariates in clinical trials, we investigated the cost in statistical power of ignoring the balance of these covariates in treatment allocation design for a logistic regression model. Based on data from a clinical trial of acute isc...

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Vydáno v:Contemp Clin Trials
Hlavní autoři: Ciolino, Jody, Zhao, Wenle, Martin, Renee’, Palesch, Yuko
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288592/
https://ncbi.nlm.nih.gov/pubmed/21078415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2010.11.005
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