HIV-1 nucleocapsid and ESCRT-component Tsg101 interplay prevents HIV from turning into a DNA-containing virus

HIV-1, the agent of the AIDS pandemic, is an RNA virus that reverse transcribes its RNA genome (gRNA) into DNA, shortly after its entry into cells. Within cells, retroviral assembly requires thousands of structural Gag proteins and two copies of gRNA as well as cellular factors, which converge to th...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Chamontin, Célia, Rassam, Patrice, Ferrer, Mireia, Racine, Pierre-Jean, Neyret, Aymeric, Lainé, Sébastien, Milhiet, Pierre-Emmanuel, Mougel, Marylène
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
Onderwerpen:
Molecular Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288153/
https://ncbi.nlm.nih.gov/pubmed/25488808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1232
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