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Requirements for nucleocapsid-mediated regulation of reverse transcription during the late steps of HIV-1 assembly

HIV-1 is a retrovirus replicating within cells by reverse transcribing its genomic RNA (gRNA) into DNA. Within cells, virus assembly requires the structural Gag proteins with few accessory proteins, notably the viral infectivity factor (Vif) and two copies of gRNA as well as cellular factors to conv...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Racine, Pierre-Jean, Chamontin, Célia, de Rocquigny, Hugues, Bernacchi, Serena, Paillart, Jean-Christophe, Mougel, Marylène
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895152/
https://ncbi.nlm.nih.gov/pubmed/27273064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27536
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