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Requirements for nucleocapsid-mediated regulation of reverse transcription during the late steps of HIV-1 assembly

HIV-1 is a retrovirus replicating within cells by reverse transcribing its genomic RNA (gRNA) into DNA. Within cells, virus assembly requires the structural Gag proteins with few accessory proteins, notably the viral infectivity factor (Vif) and two copies of gRNA as well as cellular factors to conv...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Racine, Pierre-Jean, Chamontin, Célia, de Rocquigny, Hugues, Bernacchi, Serena, Paillart, Jean-Christophe, Mougel, Marylène
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4895152/
https://ncbi.nlm.nih.gov/pubmed/27273064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27536
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