HIV-1 nucleocapsid and ESCRT-component Tsg101 interplay prevents HIV from turning into a DNA-containing virus

HIV-1, the agent of the AIDS pandemic, is an RNA virus that reverse transcribes its RNA genome (gRNA) into DNA, shortly after its entry into cells. Within cells, retroviral assembly requires thousands of structural Gag proteins and two copies of gRNA as well as cellular factors, which converge to th...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Chamontin, Célia, Rassam, Patrice, Ferrer, Mireia, Racine, Pierre-Jean, Neyret, Aymeric, Lainé, Sébastien, Milhiet, Pierre-Emmanuel, Mougel, Marylène
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288153/
https://ncbi.nlm.nih.gov/pubmed/25488808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1232
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