HIV-1 nucleocapsid and ESCRT-component Tsg101 interplay prevents HIV from turning into a DNA-containing virus

HIV-1, the agent of the AIDS pandemic, is an RNA virus that reverse transcribes its RNA genome (gRNA) into DNA, shortly after its entry into cells. Within cells, retroviral assembly requires thousands of structural Gag proteins and two copies of gRNA as well as cellular factors, which converge to th...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Chamontin, Célia, Rassam, Patrice, Ferrer, Mireia, Racine, Pierre-Jean, Neyret, Aymeric, Lainé, Sébastien, Milhiet, Pierre-Emmanuel, Mougel, Marylène
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Molecular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288153/
https://ncbi.nlm.nih.gov/pubmed/25488808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1232
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