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Nucleocapsid mutations turn HIV-1 into a DNA-containing virus

Retroviruses replicate by converting their positive sense genomic RNA into double-stranded DNA that is subsequently integrated into the host genome. This conversion is catalyzed by reverse transcriptase (RT) early after virus entry into the target cell and is chaperoned by the nucleocapsid protein (...

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Hlavní autoři: Houzet, Laurent, Morichaud, Zakia, Didierlaurent, Ludovic, Muriaux, Delphine, Darlix, Jean-Luc, Mougel, Marylène
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2367716/
https://ncbi.nlm.nih.gov/pubmed/18296486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn069
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