Intracellular HIV-1 Gag localization is impaired by mutations in the nucleocapsid zinc fingers

BACKGROUND: The HIV-1 nucleocapsid protein (NC) is formed of two CCHC zinc fingers flanked by highly basic regions. HIV-1 NC plays key roles in virus structure and replication via its nucleic acid binding and chaperoning properties. In fact, NC controls proviral DNA synthesis by reverse transcriptas...

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Main Authors: Grigorov, Boyan, Décimo, Didier, Smagulova, Fatima, Péchoux, Christine, Mougel, Marylène, Muriaux, Delphine, Darlix, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976323/
https://ncbi.nlm.nih.gov/pubmed/17683545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-54
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