HIV-1 nucleocapsid and ESCRT-component Tsg101 interplay prevents HIV from turning into a DNA-containing virus

HIV-1, the agent of the AIDS pandemic, is an RNA virus that reverse transcribes its RNA genome (gRNA) into DNA, shortly after its entry into cells. Within cells, retroviral assembly requires thousands of structural Gag proteins and two copies of gRNA as well as cellular factors, which converge to th...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chamontin, Célia, Rassam, Patrice, Ferrer, Mireia, Racine, Pierre-Jean, Neyret, Aymeric, Lainé, Sébastien, Milhiet, Pierre-Emmanuel, Mougel, Marylène
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288153/
https://ncbi.nlm.nih.gov/pubmed/25488808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1232
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