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A Bifurcated Proteoglycan Binding Small Molecule Carrier for siRNA Delivery

A wider application of siRNA- and miRNA- based therapeutics is restricted by the currently available delivery systems. We have designed a new type of small molecule carrier (SMoC) system for siRNA modeled to interact with cell surface proteoglycans. This bifurcated SMoC has similar affinity for the...

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Dades bibliogràfiques
Publicat a:Chem Biol Drug Des
Autors principals: Gooding, Matt, Adigbli, Derick, Edith Chan, A W, Melander, Roberta J, MacRobert, Alexander J, Selwood, David L
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286013/
https://ncbi.nlm.nih.gov/pubmed/24472581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12295
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