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A Bifurcated Proteoglycan Binding Small Molecule Carrier for siRNA Delivery
A wider application of siRNA- and miRNA- based therapeutics is restricted by the currently available delivery systems. We have designed a new type of small molecule carrier (SMoC) system for siRNA modeled to interact with cell surface proteoglycans. This bifurcated SMoC has similar affinity for the...
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| Publicado no: | Chem Biol Drug Des |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4286013/ https://ncbi.nlm.nih.gov/pubmed/24472581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12295 |
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