Topical Delivery of siRNA into Skin using SPACE-peptide Carriers

Short-interfering RNAs (siRNAs) offer a potential tool for the treatment of skin disorders. However, applications of siRNA for dermatological conditions are limited by their poor permeation across the stratum corneum of the skin and low penetration into skin’s viable cells. In this study, we report...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Control Release
Main Authors: Chen, Ming, Zakrewsky, Michael, Gupta, Vivek, Anselmo, Aaron C., Slee, Deborah H., Muraski, John A., Mitragotri, Samir
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425738/
https://ncbi.nlm.nih.gov/pubmed/24434423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.01.006
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