Topical Delivery of siRNA into Skin using SPACE-peptide Carriers

Short-interfering RNAs (siRNAs) offer a potential tool for the treatment of skin disorders. However, applications of siRNA for dermatological conditions are limited by their poor permeation across the stratum corneum of the skin and low penetration into skin’s viable cells. In this study, we report...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Chen, Ming, Zakrewsky, Michael, Gupta, Vivek, Anselmo, Aaron C., Slee, Deborah H., Muraski, John A., Mitragotri, Samir
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425738/
https://ncbi.nlm.nih.gov/pubmed/24434423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.01.006
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