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Topical Delivery of Hyaluronic Acid into Skin using SPACE-peptide Carriers

Topical penetration of macromolecules into skin is limited by their low permeability. Here, we report the use of a skin penetrating peptide, SPACE peptide, to enhance topical delivery of a macromolecule, hyaluronic acid (HA, MW: 200–325 kDa). The peptide was conjugated to phospholipids and used to p...

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Detalhes bibliográficos
Main Authors: Chen, Ming, Gupta, Vivek, Anselmo, Aaron C., Muraski, John A., Mitragotri, Samir
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128962/
https://ncbi.nlm.nih.gov/pubmed/24129342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.10.007
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