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Research progress on siRNA delivery with nonviral carriers

RNA interference is a powerful method for the knockdown of pathologically relevant genes. Small interfering RNAs (siRNAs) have been widely demonstrated as effective biomedical genetic-therapy applications for many diseases. Unfortunately, siRNA duplexes are not ideal drug-like molecules. Problems hi...

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Detalhes bibliográficos
Main Authors: Gao, Yan, Liu, Xin-Ling, Li, Xiao-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124387/
https://ncbi.nlm.nih.gov/pubmed/21720513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S17040
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