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Nonviral delivery of synthetic siRNAs in vivo
Sequence-specific gene silencing using small interfering RNA (siRNA) is a Nobel prize–winning technology that is now being evaluated in clinical trials as a potentially novel therapeutic strategy. This article provides an overview of the major pharmaceutical challenges facing siRNA therapeutics, foc...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2096447/ https://ncbi.nlm.nih.gov/pubmed/18060020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33494 |
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