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The SmgGDS splice variant SmgGDS-558 is a key promoter of tumor growth and RhoA signaling in breast cancer

Breast cancer malignancy is promoted by the small GTPases RhoA and RhoC. SmgGDS is a guanine nucleotide exchange factor that activates RhoA and RhoC in vitro. We previously reported that two splice variants of SmgGDS, SmgGDS-607 and SmgGDS-558, have different characteristics in binding and transport...

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Detaylı Bibliyografya
Yayımlandı:Mol Cancer Res
Asıl Yazarlar: Hauser, Andrew D., Bergom, Carmen, Schuld, Nathan J., Chen, Xiuxu, Lorimer, Ellen L., Huang, Jian, Mackinnon, Alexander C., Williams, Carol L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285378/
https://ncbi.nlm.nih.gov/pubmed/24197117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0362
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