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SmgGDS-607 regulation of RhoA GTPase prenylation is nucleotide dependent.
Protein prenylation involves the attachment of a hydrophobic isoprenoid moiety to the C-terminus of proteins. Several small GTPases, including members of the Ras and Rho subfamilies, require prenylation for their normal and pathological functions. Recent work has suggested that SmgGDS proteins regul...
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| Veröffentlicht in: | Biochemistry |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686180/ https://ncbi.nlm.nih.gov/pubmed/29940100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00567 |
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