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SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers

Oncogenic mutation or misregulation of small GTPases in the Ras and Rho families can promote unregulated cell cycle progression in cancer. Post-translational modification by prenylation of these GTPases allows them to signal at the cell membrane. Splice variants of SmgGDS, named SmgGDS-607 and SmgGD...

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Detalhes bibliográficos
Main Authors: Schuld, Nathan J, Hauser, Andrew D, Gastonguay, Adam J, Wilson, Jessica M, Lorimer, Ellen L, Williams, Carol L
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984317/
https://ncbi.nlm.nih.gov/pubmed/24552806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27804
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