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Splice Variants of SmgGDS Control Small GTPase Prenylation and Membrane Localization
Ras and Rho small GTPases possessing a C-terminal polybasic region (PBR) are vital signaling proteins whose misregulation can lead to cancer. Signaling by these proteins depends on their ability to bind guanine nucleotides and their prenylation with a geranylgeranyl or farnesyl isoprenoid moiety and...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975149/ https://ncbi.nlm.nih.gov/pubmed/20709748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.129916 |
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