SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers

Por Schuld, Nathan J, Hauser, Andrew D, Gastonguay, Adam J, Wilson, Jessica M, Lorimer, Ellen L, Williams, Carol L
Publicado em 2014

Splice Variants of SmgGDS Control Small GTPase Prenylation and Membrane Localization

Por Berg, Tracy J., Gastonguay, Adam J., Lorimer, Ellen L., Kuhnmuench, John R., Li, Rongshan, Fields, Alan P., Williams, Carol L.
Publicado em 2010

The SmgGDS splice variant SmgGDS-558 is a key promoter of tumor growth and RhoA signaling in breast cancer

Por Hauser, Andrew D., Bergom, Carmen, Schuld, Nathan J., Chen, Xiuxu, Lorimer, Ellen L., Huang, Jian, Mackinnon, Alexander C., Williams, Carol L.
Publicado no Mol Cancer Res (2013)

The Chaperone Protein SmgGDS Interacts with Small GTPases Entering the Prenylation Pathway by Recognizing the Last Amino Acid in the CAAX Motif

Por Schuld, Nathan J., Vervacke, Jeffrey S., Lorimer, Ellen L., Simon, Nathan C., Hauser, Andrew D., Barbieri, Joseph T., Distefano, Mark D., Williams, Carol L.
Publicado em 2014

An Adenosine-Mediated Signaling Pathway Suppresses Prenylation of the GTPase Rap1B and Promotes Cell Scattering

Por Ntantie, Elizabeth, Gonyo, Patrick, Lorimer, Ellen L., Hauser, Andrew D., Schuld, Nathan, McAllister, Donna, Kalyanaraman, Balaraman, Dwinell, Michael B., Auchampach, John A., Williams, Carol L.
Publicado no Sci Signal (2013)

The Tumor-suppressive Small GTPase DiRas1 Binds the Noncanonical Guanine Nucleotide Exchange Factor SmgGDS and Antagonizes SmgGDS Interactions with Oncogenic Small GTPases

Por Bergom, Carmen, Hauser, Andrew D., Rymaszewski, Amy, Gonyo, Patrick, Prokop, Jeremy W., Jennings, Benjamin C., Lawton, Alexis J., Frei, Anne, Lorimer, Ellen L., Aguilera-Barrantes, Irene, Mackinnon, Alexander C., Noon, Kathleen, Fierke, Carol A., Williams, Carol L.
Publicado no J Biol Chem (2016)

The tumor-suppressive small GTPase DiRas1 binds the noncanonical guanine nucleotide exchange factor SmgGDS and antagonizes SmgGDS interactions with oncogenic small GTPases.

Por Bergom, Carmen, Hauser, Andrew D., Rymaszewski, Amy, Gonyo, Patrick, Prokop, Jeremy W., Jennings, Benjamin C., Lawton, Alexis J., Frei, Anne, Lorimer, Ellen L., Aguilera-Barrantes, Irene, Mackinnon, Alexander C., Noon, Kathleen, Fierke, Carol A., Williams, Carol L.
Publicado no J Biol Chem (2016)