An Adenosine-Mediated Signaling Pathway Suppresses Prenylation of the GTPase Rap1B and Promotes Cell Scattering

During metastasis, cancer cells acquire the ability to dissociate from each other and migrate, which is recapitulated in vitro as cell scattering. The small guanosine triphosphatase (GTPase) Rap1 opposes cell scattering by promoting cell-cell adhesion, a function that requires its prenylation, or po...

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Publicado no:Sci Signal
Main Authors: Ntantie, Elizabeth, Gonyo, Patrick, Lorimer, Ellen L., Hauser, Andrew D., Schuld, Nathan, McAllister, Donna, Kalyanaraman, Balaraman, Dwinell, Michael B., Auchampach, John A., Williams, Carol L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278376/
https://ncbi.nlm.nih.gov/pubmed/23716716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003374
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