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β-Adrenergic receptors suppress Rap1B prenylation and promote the metastatic phenotype in breast cancer cells

A greater understanding of the molecular basis of breast cancer metastasis will lead to identification of novel therapeutic targets and better treatments. Rap1B is a small GTPase that suppresses the metastasis of breast cancer cells by increasing cell-cell adhesion. In breast cancer, a decrease in R...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Wilson, Jessica M, Lorimer, Ellen, Tyburski, Michael D, Williams, Carol L
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622671/
https://ncbi.nlm.nih.gov/pubmed/26209110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1070988
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