The Parathyroid Hormone-Regulated Transcriptome in Osteocytes: Parallel Actions with 1,25-Dihydroxyvitamin D(3) to Oppose Gene Expression Changes During Differentiation and to Promote Mature Cell Function

Although localized to the mineralized matrix of bone, osteocytes are able to respond to systemic factors such as the calciotropic hormones 1,25(OH)(2)D(3) and PTH. In the present studies, we examine the transcriptomic response to PTH in an osteocyte cell model and found that this hormone regulated a...

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Bibliografske podrobnosti
izdano v:Bone
Main Authors: St John, Hillary C., Meyer, Mark B., Benkusky, Nancy A., Carlson, Alex H., Prideaux, Mathew, Bonewald, Lynda F., Pike, J. Wesley
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285334/
https://ncbi.nlm.nih.gov/pubmed/25460572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.11.010
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