The Parathyroid Hormone-Regulated Transcriptome in Osteocytes: Parallel Actions with 1,25-Dihydroxyvitamin D(3) to Oppose Gene Expression Changes During Differentiation and to Promote Mature Cell Function

Although localized to the mineralized matrix of bone, osteocytes are able to respond to systemic factors such as the calciotropic hormones 1,25(OH)(2)D(3) and PTH. In the present studies, we examine the transcriptomic response to PTH in an osteocyte cell model and found that this hormone regulated a...

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Vydáno v:Bone
Hlavní autoři: St John, Hillary C., Meyer, Mark B., Benkusky, Nancy A., Carlson, Alex H., Prideaux, Mathew, Bonewald, Lynda F., Pike, J. Wesley
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285334/
https://ncbi.nlm.nih.gov/pubmed/25460572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.11.010
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