The Parathyroid Hormone-Regulated Transcriptome in Osteocytes: Parallel Actions with 1,25-Dihydroxyvitamin D(3) to Oppose Gene Expression Changes During Differentiation and to Promote Mature Cell Function

Although localized to the mineralized matrix of bone, osteocytes are able to respond to systemic factors such as the calciotropic hormones 1,25(OH)(2)D(3) and PTH. In the present studies, we examine the transcriptomic response to PTH in an osteocyte cell model and found that this hormone regulated a...

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Détails bibliographiques
Publié dans:Bone
Auteurs principaux: St John, Hillary C., Meyer, Mark B., Benkusky, Nancy A., Carlson, Alex H., Prideaux, Mathew, Bonewald, Lynda F., Pike, J. Wesley
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285334/
https://ncbi.nlm.nih.gov/pubmed/25460572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.11.010
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