The Parathyroid Hormone-Regulated Transcriptome in Osteocytes: Parallel Actions with 1,25-Dihydroxyvitamin D(3) to Oppose Gene Expression Changes During Differentiation and to Promote Mature Cell Function

Although localized to the mineralized matrix of bone, osteocytes are able to respond to systemic factors such as the calciotropic hormones 1,25(OH)(2)D(3) and PTH. In the present studies, we examine the transcriptomic response to PTH in an osteocyte cell model and found that this hormone regulated a...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Bone
المؤلفون الرئيسيون: St John, Hillary C., Meyer, Mark B., Benkusky, Nancy A., Carlson, Alex H., Prideaux, Mathew, Bonewald, Lynda F., Pike, J. Wesley
التنسيق: Artigo
اللغة:Inglês
منشور في: 2014
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285334/
https://ncbi.nlm.nih.gov/pubmed/25460572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.11.010
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