Structural basis of HIV-1 capsid recognition by PF74 and CPSF6

Upon infection of susceptible cells by HIV-1, the conical capsid formed by ∼250 hexamers and 12 pentamers of the CA protein is delivered to the cytoplasm. The capsid shields the RNA genome and proteins required for reverse transcription. In addition, the surface of the capsid mediates numerous host–...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bhattacharya, Akash, Alam, Steven L., Fricke, Thomas, Zadrozny, Kaneil, Sedzicki, Jaroslaw, Taylor, Alexander B., Demeler, Borries, Pornillos, Owen, Ganser-Pornillos, Barbie K., Diaz-Griffero, Felipe, Ivanov, Dmitri N., Yeager, Mark
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284599/
https://ncbi.nlm.nih.gov/pubmed/25518861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419945112
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