Structural basis of HIV-1 capsid recognition by PF74 and CPSF6

Upon infection of susceptible cells by HIV-1, the conical capsid formed by ∼250 hexamers and 12 pentamers of the CA protein is delivered to the cytoplasm. The capsid shields the RNA genome and proteins required for reverse transcription. In addition, the surface of the capsid mediates numerous host–...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Bhattacharya, Akash, Alam, Steven L., Fricke, Thomas, Zadrozny, Kaneil, Sedzicki, Jaroslaw, Taylor, Alexander B., Demeler, Borries, Pornillos, Owen, Ganser-Pornillos, Barbie K., Diaz-Griffero, Felipe, Ivanov, Dmitri N., Yeager, Mark
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284599/
https://ncbi.nlm.nih.gov/pubmed/25518861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419945112
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