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Helical Conformation in the CA-SP1 Junction of the Immature HIV-1 Lattice Determined from Solid-State NMR of Virus-like Particles

Maturation of HIV-1 requires disassembly of the Gag polyprotein lattice, which lines the viral membrane in the immature state, and subsequent assembly of the mature capsid protein lattice, which encloses viral RNA in the mature state. Metastability of the immature lattice has been proposed to depend...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Bayro, Marvin J., Ganser-Pornillos, Barbie K., Zadrozny, Kaneil K., Yeager, Mark, Tycko, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636003/
https://ncbi.nlm.nih.gov/pubmed/27593947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b07259
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