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Architectures of Whole-Module and Bimodular Proteins from the 6-Deoxyerythronolide B Synthase
The 6-deoxyerythronolide B synthase (DEBS) is a prototypical assembly line polyketide synthase (PKS) produced by the actinomycete Saccharopolyspora erythraea that synthesizes the macrocyclic core of the antibiotic erythromycin, 6-deoxyerythronolide B (6-dEB). The megasynthase is a 2 MDa trimeric com...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4284093/ https://ncbi.nlm.nih.gov/pubmed/24704088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.03.015 |
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