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Tumor-specific CD4(+) T cells maintain effector and memory tumor-specific CD8(+) T cells

Immunotherapies that augment antitumor T cells have had recent success for treating patients with cancer. Here we examined whether tumor-specific CD4(+) T cells enhance CD8(+) T-cell adoptive immunotherapy in a lymphopenic environment. Our model employed physiological doses of tyrosinase-related pro...

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Pubblicato in:Eur J Immunol
Autori principali: Church, Sarah E, Jensen, Shawn M, Antony, Paul A, Restifo, Nicholas P, Fox, Bernard A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283993/
https://ncbi.nlm.nih.gov/pubmed/24114780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343718
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