Peroxiredoxin II Regulates Effector and Secondary Memory CD8(+) T Cell Responses

Reactive oxygen intermediates (ROI) generated in response to receptor stimulation play an important role in cellular responses. However, the effect of increased H(2)O(2) on an antigen-specific CD8(+) T cell response was unknown. Following T cell receptor (TCR) stimulation, the expression and oxidati...

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Autori principali: Michalek, Ryan D., Crump, Katie E., Weant, Ashley E., Hiltbold, Elizabeth M., Juneau, Daniel G., Moon, Eun-Yi, Yu, Dae-Yeul, Poole, Leslie B., Grayson, Jason M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Cellular Response to Infection
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503052/
https://ncbi.nlm.nih.gov/pubmed/23055551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01559-12
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