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The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes
The amyloid precursor protein (APP) has occupied a central position in Alzheimer’s disease (AD) pathophysiology, in large part due to the seminal role of amyloid-β peptide (Aβ), a proteolytic fragment derived from APP. Although the contribution of Aβ to AD pathogenesis is accepted by many in the res...
Gorde:
| Argitaratua izan da: | Acta Neuropathol |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282969/ https://ncbi.nlm.nih.gov/pubmed/25287911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1347-2 |
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