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Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems

Alzheimer's disease (AD) is a progressive neurodegenerative disease and in its familial form is associated with mutations in the amyloid precursor protein (APP) and the presenilins (PSs). Much data regarding the interactions of APP, its proteolytic fragments and PS have been generated, expandin...

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Detalhes bibliográficos
Main Authors: Hunter, Sally, Brayne, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583130/
https://ncbi.nlm.nih.gov/pubmed/22498202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt108
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