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Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems

Alzheimer's disease (AD) is a progressive neurodegenerative disease and in its familial form is associated with mutations in the amyloid precursor protein (APP) and the presenilins (PSs). Much data regarding the interactions of APP, its proteolytic fragments and PS have been generated, expandin...

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Autors principals: Hunter, Sally, Brayne, Carol
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583130/
https://ncbi.nlm.nih.gov/pubmed/22498202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt108
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