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N-terminal acetylation and replicative age affect proteasome localization and cell fitness during aging

Specific degradation of proteins is essential for virtually all cellular processes and is carried out predominantly by the proteasome. The proteasome is important for clearance of damaged cellular proteins. Damaged proteins accumulate over time and excess damaged proteins can aggregate and induce th...

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Bibliografski detalji
Izdano u:J Cell Sci
Glavni autori: van Deventer, Sjoerd, Menendez-Benito, Victoria, van Leeuwen, Fred, Neefjes, Jacques
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282048/
https://ncbi.nlm.nih.gov/pubmed/25413350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.157354
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