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CDK1-dependent Inhibition of the E3 Ubiquitin Ligase CRL4(CDT2) Ensures Robust Transition from S Phase to Mitosis
Replication-coupled destruction of a cohort of cell cycle proteins ensures efficient and precise genome duplication. Three proteins destroyed during replication via the CRL4(CDT2) ubiquitin E3 ligase, CDT1, p21, and SET8 (PR-SET7), are also essential or important during mitosis, making their reaccum...
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| Publicat a: | J Biol Chem |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281756/ https://ncbi.nlm.nih.gov/pubmed/25411249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.614701 |
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