Regulation of the CRL4(Cdt2) ubiquitin ligase and cell cycle exit by the SCF(Fbxo11) ubiquitin ligase

F-box proteins and DCAF proteins are the substrate binding subunits of SCF (Skp1-Cul1-F-box protein) and CRL4 (Cul4-RING protein Ligase) ubiquitin ligase complexes, respectively. Using affinity purification and mass spectrometry, we determined that the F-box protein FBXO11 interacts with CDT2, a DCA...

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Hoofdauteurs: Rossi, Mario, Duan, Shanshan, Jeong, Yeon-Tae, Horn, Moritz, Saraf, Anita, Florens, Laurence, Washburn, Michael P., Antebi, Adam, Pagano, Michele
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624904/
https://ncbi.nlm.nih.gov/pubmed/23478441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.02.004
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