CDK1-dependent Inhibition of the E3 Ubiquitin Ligase CRL4(CDT2) Ensures Robust Transition from S Phase to Mitosis

Replication-coupled destruction of a cohort of cell cycle proteins ensures efficient and precise genome duplication. Three proteins destroyed during replication via the CRL4(CDT2) ubiquitin E3 ligase, CDT1, p21, and SET8 (PR-SET7), are also essential or important during mitosis, making their reaccum...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Rizzardi, Lindsay F., Coleman, Kate E., Varma, Dileep, Matson, Jacob P., Oh, Seeun, Cook, Jeanette Gowen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281756/
https://ncbi.nlm.nih.gov/pubmed/25411249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.614701
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