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HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models

The efficacy of hormonal therapies for advanced estrogen receptor-positive breast cancers is limited by the nearly inevitable development of acquired resistance. Efforts to block the emergence of resistance have met with limited success, largely because the mechanisms underlying it are so varied and...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Whitesell, Luke, Santagata, Sandro, Mendillo, Marc L., Lin, Nancy U., Proia, David A., Lindquist, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280614/
https://ncbi.nlm.nih.gov/pubmed/25489079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421323111
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