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HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models

The efficacy of hormonal therapies for advanced estrogen receptor-positive breast cancers is limited by the nearly inevitable development of acquired resistance. Efforts to block the emergence of resistance have met with limited success, largely because the mechanisms underlying it are so varied and...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Whitesell, Luke, Santagata, Sandro, Mendillo, Marc L., Lin, Nancy U., Proia, David A., Lindquist, Susan
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280614/
https://ncbi.nlm.nih.gov/pubmed/25489079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421323111
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