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HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models

The efficacy of hormonal therapies for advanced estrogen receptor-positive breast cancers is limited by the nearly inevitable development of acquired resistance. Efforts to block the emergence of resistance have met with limited success, largely because the mechanisms underlying it are so varied and...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Whitesell, Luke, Santagata, Sandro, Mendillo, Marc L., Lin, Nancy U., Proia, David A., Lindquist, Susan
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280614/
https://ncbi.nlm.nih.gov/pubmed/25489079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421323111
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