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Genetic Architecture of Hsp90-Dependent Drug Resistance

Hsp90 potentiates the evolution of azole resistance in the model yeast Saccharomyces cerevisiae and the opportunistic pathogen Candida albicans via calcineurin. Here, we explored effectors downstream of calcineurin regulating this Hsp90-dependent trait. Using S. cerevisiae erg3 mutants as a model, w...

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Bibliografske podrobnosti
Main Authors: Cowen, Leah E., Carpenter, Anne E., Matangkasombut, Oranart, Fink, Gerald R., Lindquist, Susan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1694807/
https://ncbi.nlm.nih.gov/pubmed/17056742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00274-06
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